研究兴趣 免疫分析,抗原抗体制备,生物学效应研究 环境监测与分析,食品检测新方法 纳米药物载体定量与可视化 主持科研项目 4. 基于免疫学的纳米颗粒的定量检测及生物学效应研究(国家自然科学基金,2012-2015),项目负责人 3. 动物源性食品中环境激素的快速检测新方法的建立与应用(安徽省高校自然科学基金重点项目,2011-2013),项目负责人 2. 酞酸酯类环境激素分子生物学检测新技术研究(安徽省自然科学基金项目,2006),项目负责人 1. 生物大分子有机纳米荧光探针的制备及其应用(安徽省博士后科研经费资助项目, 2005),项目负责人 主持教研项目 化学专业设计性实验的教学探索与实践(安徽省级教学研究重点项目,2010),项目负责人 讲授课程 《分析化学》《仪器分析》《基础化学实验》《综合化学实验》《分析化学实验》等 获奖情况 2008年获必赢线路检测3003教学优秀一等奖 代表性论文 17. Lei Li, Mingcui Zhang*. Development of immunoassays for the determination of phthalates. Food and Agricultural Immunology, 2020, 31(1): 303-316. DOI: 10.1080/09540105.2020.1721439 16. Lei Li, Zhongyu Lian, Xi Yan, Meng Xia, Mingcui Zhang*. An evaporation induced self-assembly approach to prepare polymorphic carbon dot fluorescent nanoprobes for protein labeling, Chemical Communications, 2018, 54, 13123-13126.DOI: 10.1039/c8cc05860a 15. Mingcui Zhang*, Wentong Hong, Xiayu Wu, Yue Zhang, Fengzhu Li and Su-Qing Zhao. A highly sensitive and direct competitive enzyme-linked immunosorbent assay for the detection of di-(2-ethylhexyl) phthalate (DEHP) in infant supplies. Analytical Methods, 2015, 7(13), 5441-5446. DOI: 10.1039/C5AY00207A 14. Durga Pokharel, Suntara Fueangfung, Mingcui Zhang, Shiyue Fang*. Peptide and peptide nucleic acid syntheses using a DNA/RNA synthesizer. Biopolymers, 2014,102(6): 487-493. DOI: 10.1002/bip.22574 13. Mingcui Zhang, Durga Pokharel, Shiyue Fang*. Purification of Synthetic Peptides Using a Catching Full-Length Sequence by Polymerization Approach. Organic Letters, 2014,16 (5), 1290-1293. DOI: 10.1021/ol403426u 12. Mingcui Zhang*, Yue Wang, Xiaona Yu, Yurong Hu & Shaohui Liu. Rapid monitoring of dicyclohexyl phthalate in foods using the direct competitive ELISA. Food and Agricultural Immunology, 2014, 25(2), 229-242. DOI:10.1080/09540105.2013.768964 11. Mingcui Zhang*, Xiaona Yu, Yue Wang, Yurong Hu, Shaohui Liu. A Highly Sensitive Indirect Competitive Enzyme-linked Immunosorbent Assay (ic-ELISA) by Antigen-coated for Diethyl Phthalate Analysis in Foods. Food Analytical Methods, 2013, 6:1223-1228. DOI: 10.1007/s12161-012-9529-9 10. Mingcui Zhang*, Yurong Hu, Shaohui Liu, Ying Cong, Bolin Liu, Lun Wang*. A highly sensitive enzyme-linked immunosorbent assay for the detection of dipropyl phthalate in plastic food contact materials. Food and Agricultural Immunology, 2013, 24:2, 165-177. DOI:10.1080/09540105.2012.670615 9. Mingcui Zhang*, Yurong Hu, Shaohui Liu, Ying Cong,Bolin Liu, Lun Wang*.Rapid Monitoring of Dipropyl phthalate in Food Samples Using a Chemiluminescent Enzyme Immunoassay. Food Analytical Methods, 2012, 5:1105–1113. DOI: 10.1007/s12161-011-9346-6 8. Mingcui Zhang*,Shaohui Liu, Huisheng Zhuang*,Yurong Hu. Determination of Dimethyl Phthalate in Environment Water Samples by a Highly Sensitive Indirect Competitive ELISA. Applied Biochemistry and Biotechnology, 2012, 166, 436-445. DOI: 10.1007/s12010-011-9439-0 7. Mingcui Zhang*, Bolin Liu, Ying Cong, Shaohui Liu, Yurong Hu. Development of highly specific fluorescence immunoassay and enzyme-linked immunosorbent assay for detection of dimethyl phthalate in water samples. Food and Agricultural Immunology, 2011, 22(4), 297-309. DOI: 10.1080/09540105.2011.575124 6. Mingcui Zhang*, Ying Cong, Yali Sheng, Bolin Liu. A direct competitive enzyme-linked immunosorbent assay by antibody coated for diethyl phthalate analysis. Analytical Biochemistry, 2010, 406 (1), 24-28. DOI: 10.1016/j.ab.2010.06.040 5. Mingcui Zhang*, Yali Sheng. An Indirect Competitive Fluorescence Immunoassay for Determination of Dicyclohexyl Phthalate in Water Samples. Journal of Fluorescence, 2010, 20(6), 1167-1173. DOI 10.1007/s10895-010-0663-8 4. Mingcui Zhang, Qionge Wang, Huisheng Zhuang*. Determination of Dibutyl o-Phthalate by Antigen-Coated Competitive Fluorescence Immunoassay. Analytical Letters, 2007, 40(1), 127- 137 3. Mingcui Zhang, Qionge Wang, Huisheng Zhuang*. A novel competitive fluorescence immunoassay for the determination of dibutyl phthalate. Analytical and Bioanalytical Chemistry, 2006, 386(5), 1401-1406 2. 张明翠, 庄惠生*, 郎庆. 环境激素邻苯二甲酸二丁酯免疫检测Ⅱ―抗体的制备. 应用化学, 2007, 24(5): 530-533 1. 张明翠, 庄惠生*, 郎庆. 邻苯二甲酸二丁酯免疫检测Ⅰ:人工抗原的制备及表征. 应用化学, 2006,23(8): 850-853 授权及转让专利 13. 张明翠, 夏濛. 一种检测叶酸功能化二氧化硅靶向纳米药物载体的方法. 中国发明专利, 专利号:ZL 201711150940.9 12. 张明翠, 闫希. 一种PSI-OAm-NAPI两亲聚合纳米材料的定量检测方法 发明. 中国发明专利, 专利号:ZL 201710489336.2 11. 张明翠, 夏濛. 一种叶酸功能化二氧化硅靶向纳米药物载体的定量检测方法. 中国发明专利, 专利号:ZL 201710489323.5 10. 张明翠, 夏濛. 一种基于直接竞争荧光免疫法定量检测叶酸功能化二氧化硅靶向纳米药物载体的方法. 中国发明专利, 专利号:ZL201710489337.7 9. 张明翠, 闫希. 一种基于痕量荧光免疫定量检测PSI-OAm-NAPI两亲聚合纳米药物载体的方法. 中国发明专利, 专利号:ZL 201710489326.9 8. 张明翠, 沈碧. 一种氧化葡萄糖包被的四氧化三铁磁性纳米材料的定量方法. 中国发明专利, 专利号:ZL 201710044829.5 7. 张明翠, 曹以婷. 一种基于间接竞争酶联免疫法定量检测油胺枝接聚琥珀酰亚胺高分子纳米药物载体的方法. 中国发明专利, 专利号:ZL 201710051804.8 6. 张明翠, 张月. 一种基于间接竞争酶联免疫法定量检测80nmAuNPs的方法. 中国发明专利, 专利号:ZL 201510567972.3 5. 张明翠, 吴瑕玉. 一种50nm银粒子的定量检测方法. 中国发明专利, 专利号:ZL 201410513013.9 4. 张明翠, 洪文童. 一种邻苯二甲酸丁基苄酯半抗原衍生物及制备方法、邻苯二甲酸丁基苄酯的检测方法. 中国发明专利, 专利号:ZL 201410512584.0 3. 张明翠, 洪文童. 一种邻苯二甲酸丁基苄酯半抗原衍生物及制备方法. 中国发明专利, 专利号:ZL 201410512359.7 2. 张明翠,钟君亚. 邻苯二甲酸(2-乙基己)酯的间接竞争酶联免疫法检测方法. 中国发明专利, 专利号:ZL 201310675076.X (已转让) 1. 张明翠, 孙锦文. 一种测试痕量特定粒径纳米金粒子的方法. 中国发明专利, 专利号:ZL 201310722275.1 论 著 教育部“十五”国家级规划教材, 化学实验(上). 北京:高等教育出版社出版(ISBN:7-04-011969-2), 2003年, 参编; 第二版(2015年),副主编 |