1. 芳炔HDDA的串联环化反应

2. 金属催化芳香杂环碳氢键活化

3. 绿色天然有机化学

主持项目

1.“多烯炔去氢芳构化构筑复杂分子骨架的Domino反应研究”，国家自然科学基金，项目号：22071001，63万，起止年月：2021.01–2024.12，项目负责人。

2. “多官能化复杂芳香功能化合物简洁合成方法学研究”，国家自然科学基金，项目号：21572002，65万，起止年月：2016.01–2019.12，项目负责人。

3. “过渡金属催化的烯丙基化及多重烯炔连续Domino反应构建几种环状复杂体系化合物研究”，国家自然科学基金，项目号：21272005，80万，起止年月：2013.01–2016.12，项目负责人。

4. “Podophyllotoxin和Conidendrin骨架及其衍生物的高效合成方法研究”，国家自然科学基金，项目号：21072003，36.0万，2011–2013年,项目负责人。

5. “芳香杂环C-H键活化构筑多环有机物的Domino反应研究”，国家自然科学基金，项目号：20872002，35.0万，2009–2011年，项目负责人。

6. “钯、铑、镍催化活性丙烯酰基在离子液体中的选择性成环偶联反应研究”，国家自然科学基金，项目号：20572001，16.0万(含学校配套经费)，2006–2007年，项目负责人。

7. 安徽省高等学校“十五”优秀人才计划学科带头人基金，3.2万，2005–2008年，项目负责人。

代表性成果

1. "Fully Substituted Conjugate Benzofuran Core: Multiyne Cascade Coupling and Oxidation of Cyclopropenon", Liangliang Yao, Qiong Hu*, Li Bao, Wenjing Zhu, and Yimin Hu*, Org. Lett. 2021, 23, 4971-4975.

2. "Access to Benzoxazepines and Fully Substituted Indoles via HDDA Coupling", Xiaojie Zheng, Baohua Liu, Feihu Yang, Qiong Hu, Liangliang Yao, and Yimin Hu*, Org. Lett. 2020, 22, 956-959.

3. "Phenanthrenes/dihydrophenanthrenes: the selectivity controlled by different benzynes and allenes", Liangliang Yao, Bo Fang, Qiong Hu, Yu Lei, Li Bao and Yimin Hu*, Chem. Commun. 2020, 56, 15185-15188.

4. "C–O/C–S difunctionalized benzene derivatives via multicomponent coupling of tetraynes", Liangliang Yao, Qiong Hu, Yu Lei, Li Bao and Yimin Hu*, Org. Chem. Front. 2020, 7, 3633-3637.

5. "One-Step Synthesis of the Benzocyclo[penta- to octa-]isoindole Core", Yimin Hu*, Chenli Yu, Dong Ren, Qiong Hu, Lidong Zhang, Dong Cheng, Angew. Chem. Int. Ed. 2009, 48, 5448-5451.

6. "Direct methylation and carbonylation of in situ generated arynes via HDDA-Wittig coupling", Baohua Liu,Chunyan Mao,Qiong Hu,Liangliang Yao,Yimin Hu*, Org. Chem. Front. 2019, 6, 2788-2791.

7. "Versatile Dibenzothio[seleno]phenes via Hexadehydro-Diels–Alder Domino Cyclization", Baohua Liu, Qiong Hu, Yinshan Wen, Bo Fang, Xiaoliang Xu, Yimin Hu*, Front. Chem. 2019, 374.

8. "Fused Multifunctionalized Dibenzoselenophenes from Tetraynes", Yimin Hu*, Jie Ma, Lidong Li, Qiong Hu, Shuang Lv, Baohua Liu, Shaowu Wang*, Chem. Commun. 2017, 53, 1542-1545.                            

9. "Direct Access to Fused Salicylaldehydes and Salicylketones from Tetraynes", Yimin Hu*, Yadong Hu, Qiong Hu, Jie Ma, Shuang Lv, Baohua Liu, Shaowu Wang*, Chem. Eur. J. 2017, 23, 4605-4072.                            

10. "Fused Multifunctionalized Chromenes from Tetraynes and α,β-Unsaturated Aldehydes", Xiangzhen Meng, Shuang Lv, Dong Cheng, Qiong Hu, Jie Ma, Baohua Liu, Yimin Hu*, Chem. Eur. J. 2017, 23, 6264-6271.  

11. "Fused Multifunctionalized Isoindole-1,3-diones via the Coupled Oxidation of Imidazoles and Tetraynes", Qiong Hu, Lidong Li, Fei Yin, Hao Zhang, Yadong Hu, Baohua Liu and Yimin Hu*, RSC Adv. 2017, 7, 49810-49816.                            

12. "Synthesis of a Type of Bridged Heterocycles via Tetraynes", Xiangzhen Meng, Dong Cheng*, Shuang Lv, Jie Ma, Yimin Hu*, Heterocycles 2017, 94, 2111-2124.          

13. "Convenient One-Step Construction of Yne-Functionalized Aryl Halides through Domino Cyclization from Tetraynes", Hao Zhang, Qiong Hu, Lidong Li, Yimin Hu*, Pingping Zhou, Xiaorong Zhang, Haifeng Xie, Shaowu Wang*, Chem. Commun. 2014, 25, 3335-3337.                            

14. "One-Step Synthesis of Diazaspiro[4.5]decane Scaffolds with Exocyclic Double Bonds", Lidong Li, Qiong Hu, Pingping Zhou, Haifeng Xie, Xiaorong Zhang, Hao Zhang, Yadong Hu, Fei Yin, Yimin Hu*, Org. Biomol. Chem. 2014, 12, 5356-5359.                            

15. "Domino Access to Yne-functionalized Benzoisoindole from Triynes", Lidong Li, Qiong Hu, Pingping Zhou, Haifeng Xie, Xiaorong Zhang, Hao Zhang, Hua Wang, Yimin Hu*, Synthesis 2014, 46, 1547-1554.    

16. "Fused Benzo[b]fluorenols: Palladium-Catalyzed Intramolecular Dehydroaromatization and Carbonyl Reduction", Quansheng Zhao, Qiong Hu, Lei Wen, Min Wu, Yimin Hu*, Adv. Synth. Catal. 2012, 354, 2113-2116.                            

17. "Synthesis of highly substituted dihydropyrrolophenanthridine derivatives by tandem reaction", Yimin Hu*, Tao Zhu, Xiaolong Mu, Quansheng Zhao, Tao Yu, Lei Wen, Yulong Zhang, MinWu, Hao Zhang, Tetrahedron 2012, 68, 311-318.                            

18. "Fused Phenanthridines: Domino Cyclization of 1,6-Diynes with Bromo(iso)quinoline", Yimin Hu*, Yongjie Sun, Jiping Hu, Tao Zhu, Tao Yu, Quansheng Zhao, Chem. Asian J. 2011, 6, 797-800.                            

19. "Construction of 3-Allyliodene-4-vinyltetrahydrofurans and 3-Allylidene-4-vinylpyrrolidines Via Sequential Domino Allylation/Olefination of CC Triple Bonds", Tuanjie Meng, Yimin Hu*, Quansheng Zhao, Tao Yu, and Shaowu Wang*, Tetrahedron 2011, 67, 8710-8716.

20. "Efficient Activation of Aromatic C-H Bonds for Fused Polyaromatic Hydrocarbon Construction", Yimin Hu*, Hao Yao, Yongjie Sun, Jing Wan, Xiangang Lin, Tao Zhu, Chem. Eur. J. 2010, 16, 7635-7641.                      

21. "Efficient Construction of Tri- and Tetracyclic Heterocycles from Linear 1,6-Dienes by a Domino Reaction", Yimin Hu*, Fengfa Song, Fenghua Wu, Dong Cheng, and Shaowu Wang*, Chem. Eur. J. 2008, 14, 3110-3117.                          

22. "Rapid construction of five contiguous stereocenters in a multi-cascade reaction", Yimin Hu*, Ying Ouyang, Yuan Qu, Qiong Hu and Hao Yao, Chem. Commun. 2009, 4575-4577.                            

23. "Tuned C-H Functionalization to Construct the Skeleton of Aza-Podophyllotoxin/Aza-Conidendrin via Domino Cyclization", Yimin Hu*, Yuan Qu, Fenghua Wu, Jinghan Gui, Yun Wei, Qiong Hu and Shaowu Wang*, Chem. Asian. J. 2010, 5, 309-314.                          

24. "Efficient Construction of Five-membered Aromatic and Nonaromatic Heterocycles from 1,6-Enynes by a Palladium-Catalyzed Domino Coupling/Cycloisomerization Process", Tuanjie Meng, Yimin Hu*, and Shaowu Wang*, J. Org. Chem. 2010, 75, 582-588.                          

25. "Palladium-Catalyzed C-C Coupling/C-H Activation: Formation of Isoindolinone-Fused Heterocyclic Compounds", Yimin Hu*, Dong Ren, Lidong Zhang, Xiangang Lin, Jing Wan, Eur. J. Org. Chem. 2010, 4454-4459.                          

26. "Coupling/Cyclization of 1,6-Enynes with Aryl Halides: an Efficient and General Route for the Synthesis of Functionalized Hexahydroindole and Hexahydrobenzofuran Derivatives", Tuanjie Meng, Yimin Hu*, Yongjie Sun, Tao Zhu, and Shaowu Wang*, Tetrahedron 2010, 8648-8653.                          

27. "A Convenient Domino Synthesis of 4,9-Diphenyl-2,3-dihydro-1H-benzo[f]iso-indole Derivatives", Yimin Hu*, Xiangang Lin, Tao Zhu, Jing Wan, Yongjie Sun, Quansheng Zhao, Tao Yu, Synthesis 2010, 3467-3473.  

28. "Palladium-Catalyzed Cyclization of Benzyl Halides with Diethyl Diallylmalonate", \ Yimin Hu, Jie Zhou, Hongzhen Lian, Chengjian Zhu, Yi Pan*, Synthesis (Issue 8, 1177-1180, 2003).                          

29. "Palladium-catalyzed cascade reaction of N-allyl-N-(2-butenyl)-p–toluenesulfon amide with benzyl halides″, Yimin Hu, Jie Zhou, Xiangtian Long, Jianlin Han, Chenjian Zhu, Yi Pan*, Tetrahedron Lett. 2003, 44, 5009-5010.                        

30. "Palladium-catalyzed cascade reaction of N, N-diallylbenzoylamide with benzyl halides", Yimin Hu, Yu Zhang, Jianlin Han, Chengjian Zhu, Yi Pan*, Chin. Chem. Lett. 2003, 14, 771-772.

31. "Synthesis and Disproportionation of Mixed Ligand Indium Organometallics Involving Ethyl and β -Diketonate Chelate Ligands", Yimin Hu, Xiaohua Huang, Zhongwen Ye*, Xiuran Wang, Jiashan Gu, Chinese J. Chem. 2001, 19, 109-112.

会议论文

1. "Fused multifunctionalized dibenzoselenophenes from tetraynes", Baohua Liu and Yimin Hu*, "4th European Chemistry Congress" (Invited Oral Lecture), (May 11-13, 2017, Barcelona, Spain, 2017).

2. "ONSTRUCTION OF CONDENSED NUCLEUS BY PALLADIUM-CATALYZED DOMINO CYCLIZATION", Lidong Li and Yimin Hu*, The Collaborative Conference on Organic Synthesis (CCOS)Graduate University of Science and Technology (GUST) (Invited Oral Lecture), (March 13-17, Hanoi, Vietnam, 2017)

3. "Efficient Construction of Fused Heterocycles by Palladium-Catalyzed C-H Activation Domino Reaction″, Qiong Hu, Dong Ren, Lidong Zhang, Tao Zhu, Yongjie Sun and Yimin Hu*, The 2010 International Conference on Pure and Applied Chemistry (Oral Presentation), (July 25-30, Mauritius, 2010).

4. "Disproportionation of Indium Organometallics Involving Ethyl and Chelate Ligands″, Yimin Hu, Xiaohua Huang, Zhongwen Ye*, Xiuran Wang, Baohui Du, The 19th IUPAC International Conference on Organometallic Chemistry, (July 23-28, Shanghai China, PS056, 2000).

5. “构筑苯并环化异吲哚骨架的Domino反应研究”, 万静, 林先刚, 姚浩, 胡益民*, 第六届全国有机化学会议, P775, 中国, 西安, 2009年8月17-20日.

6. “形成吲哚化合物及其衍生物反应中的钯氧化催化研究”，孟团结, 胡益民*, 朱涛, 孙永杰, 王绍武*, 第六届全国有机化学会议, P774, 中国, 西安, 2009年8月17-20日.

7.“在离子液体中进行的电化学支持的Heck反应”, 曲媛, 卢嘉, 桂敬汉, 胡益民*, 褚道葆*, 第五届全国有机化学会议, P330, 中国, 郑州, 2007年8月18-22日.

8. “镍催化的电化学偶联反应”, 卢嘉, 曲媛, 桂敬汉, 褚道葆*, 胡益民*, 第五届全国有机化学会议, P331, 中国, 郑州, 2007年8月18-22日.

9. “微波在钯催化下的偶联成环反应中的应用”, 胡益民*, 张霞, 曲媛, 吴凤华, 程东, 第四届全国有机化学会议(口头报告), P96, 中国, 昆明, 2005年8月8-11日.

10. “二烯丙基丙二酸二乙酯与苄基卤化物的钯催化下的成环反应”, 胡益民, 潘毅*, 第二届全国有机化学会议(口头报告), 中国, 杭州, 2001年8月5-8日.

11. “有机铟衍生物的合成研究”, 胡益民, 周虹屏, 叶钟文, 王修然, 第十届全国金属有机化学会议, P218, 中国, 长沙, 1998年10月7-11日.

12. “三乙基铟的合成研究”, 胡益民, 黄小华, 顾家山, 王修然, 叶钟文, 第十届全国金属有机化学会议, P219, 中国, 长沙, 1998年10月7-11日.

专 利

1. 一种带环外双键二氮杂螺[4.5]癸烷衍生物及其合成方法, 201410293047.1, 授权日期: 2017.1.4

2.一种芴酮衍生物及其制备以及合成芴酮的氧化还原方法, 201410725048.9, 授权日期: 2017.1.4

3. 一种肉桂酸酯类衍生物及其制备方法, 201410728360.3, 授权日期: 2017.1.4 

4. 一种安息香肟衍生物及其制备方法, 201410728358.6, 授权日期: 2017.1.11

5. 一种芳卤衍生物及其合成方法, 201410293039.7, 授权日期: 2017.4.12 

6. 一种1,5-二羰基衍生物及其制备方法, 201510896115.8, 授权日期: 2017.6.16

7. 一种二苯碲醚衍生物及其制备方法, 201610070522.8, 授权日期: 2017.10.25