所受教育
· 学士 （1983年） 必赢线路检测3003
· 硕士 （1994年） 中国科学技术大学
· 博士 （2004年） 厦门大学
职称职位
· 1983年-现在 必赢线路检测3003 助教 讲师 副教授 教授 博士生导师
· 2004年-2015年 必赢线路检测3003 必赢线路检测3003 副院长 院长
主持项目
1. 纳米晶体的功能化修饰及化学发光研究， 99 年必赢线路检测3003科研专项基金
2. 纳米晶体的功能化修饰及其在生物分析中的应用， 2001 年安徽省教育厅自然科学基金重点项目
3. 无机纳米粒子作为红区荧光探针的研究 , 2004 年必赢线路检测3003博士科研资助计划项目
4. 物种敏感量子点新型荧光探针的制备及应用 , 2005 年国家自然科学基金 （ 20575002 ）
5. 高选择性量子点传感系统的构建与应用, 2007 年安徽省自然科学基金 （ 070416239 ）
6. 量子点尺寸以依赖荧光猝灭研究及其分析应用，2008 年国家自然科学基金 （ 20875003 ）
7. 分析物诱导的零维和一维CdTe纳米结构间的快速转换与荧光偏振传感研究，2011年国家自然科学基金 （21175003）
8. 高量子产率近红区发射碳点的研制及分析应用，2013年国家自然科学基金（21375003）
研究领域
1. 化学发光新体系研究
2. 有机荧光探针合成、性质及应用研究
3. 纳米荧光探针合成、性质及应用研究
4. 荧光传感研究
讲授课程
《分析化学》，《仪器分析》，《近代仪器分析》，《化学发光分析》，《专业英语》
获奖情况
1. 1995 年获校首届“皖泰优秀教学奖”
2. 1997 年《发光分析》（合作）获安徽省高等学校科学技术进步三等奖
3. 2000 年《 ICP 仿真实验系统》（合作）获 CIETE 全国多媒体教育软件大奖赛三等奖
4. 2000 年《分析化学三级教学模式研究》（合作）获安徽省教学成果三等奖。
发表论文
1. Changqin Zhu， Donghui Li, Qingzhi Zhu, Hong Zheng, Qiuying Chen, Huanghao Yang, Jingou Xu*, Determination of proteins at nanogram levels by their quenching effect on large particle scattering of colloidal silver chloride, Freseniu's J. Anal. Chem., 2000, 366 (8): 863-868.
2. Changqin Zhu， Donghui Li, Qingzhi Zhu, Hong Zheng, Qiuying Chen, Jingou Xu*, Application of manganese tetrasulfonatophthalocyanine as a new mimetic peroxidase in the determination of hydrogen peroxide in marine surface water samples with phydroxyphenyl acetic acid as a substrate, Anal. Sci., 2000, 16 (3): 253-256
3. Yongxin Li, Danhua Zhao, Changqin Zhu*, Lun Wang, Jingou Xu, Determination of proteins at nanogram levels by their quenching effect on the chemiluminescence reaction between luminol and hydrogen peroxide with manganese tetrasulfonato phthalocyanine as a new catalyst, Anal. & Bioanal. Chem., 2002, 374 (3): 395-398
4. Lun Wang, Yongxin Li, Danhua Zhao, Changqin Zhu*, A novel flow-infection chemiluminescence method to determination of glutathione using the reaction of luminol with hydrogen peroxide, Microchim. Acta , 2003, 141(1-2): 41-45
5. Changqing Zhu* , Shujuan Zhuo, Yongxin Li, Lun Wang, Danhua Zhao, Jinlong Chen, Yuqin Wu, Determination of nucleic acids with tetra- (N-hexadecyl- pyridiniumyl) porphyrin sensitized by cetyltrimethylammonium bromide (CTMAB) using a rayleigh light- scattering technique, Spectrochim. Acta , 2004, 60 (4): 959-964
6. Chang Qing Zhu*, Dan Hua Zhao, Jin Long Chen, Yong Xin Li, Le Yu Wang, Lun Wang, Yun You Zhou, Shu Juan Zhuo, Yu Qin Wu, Application of L-cysteine-capped nano-ZnS as a Fluorescence Probe for the determination of proteins, Anal. & Bioanal. Chem. , 2004, 378: 811-815
7. Chang-Qing Zhu*, Yu-Qin Wua, Hong Zheng, Jin-Long Chena, Shu-Juan Zhuoa, Yong-Xin Li, Spectrophotometric method for the direct determination of anionic surfactant sodium dodecyl benzenesulphonate (SDBS) using a hydrophobic Near-infrared (NIR) cationic cyanine dye without solvent extraction, Anal.Lett., 2004, 37: 725-737
8. Chang-Qing Zhu*, Yu-Qin Wu, Hong Zheng, Jin-Long Chen, Shu-Juan Zhuo, Yong-Xin Li, Fluorescence enhancement method for measuring anionic surfactant sodium dodecyl benzenesulphonate (SDBS) with a hydrophobic cyanine dye, Anal. & Bioanal. Chem., 2004, 379: 730-734
9. Chang-Qing Zhu, Shu-Juan Zhuo, Jin-Long Chen, Yu-Qin Wu, Yong-Xin Li, Dong-Hui Li, Hong Zheng, Jin-Gou Xu* , A kinetic fluorometric method for the determination of nucleic acids using a ternary equilibrium system of nucleic acids - iron ( Ⅲ ) tetracarboxy phthalocyanine- poly-lysine coupled with the oxidation reaction between hydrogen peroxide and DL-tyrosine, Anal.Chim.Acta , 2004, 514 (2): 247-252
10. Shujuan Zhuo, Jinlong Chen, Hong Zheng, Yuqin Wu, Changqing Zhu* , Determination of nucleic acids based on shifting the association equilibrium between tetracarboxy aluminum phthalocyanine and tetra- (N-hexadecyl- pyridiniumyl) porphyrin, Talanta, 2004, 64: 528-533
11. Chang-Qing Zhu, Shu-Juan Zhuo, Hong Zheng, Jin-Long Chen, Dong-Hui Li, Shun-Hua Li, Jin-Gou Xu*, Fluorescence enhancement method for the determination of nucleic acids using cationic cyanine as a fluorescence probe, Analyst, 2004, 129: 254-258
12. Changqing Zhu, Hong Zheng, Donghui Li, Shunhua Li and Jingou Xu*, Near-infrared hydrophobic probes as molecular light switch for CMC determination of Triton X-100 solution, J. Chinese Chemistry , 2004, 22:1319-1324
13.Changqing Zhu, Hong Zheng, Donghui Li, Shunhua Li and Jingou Xu*, Fluorescence quenching method for the determination of sodium dodecyl sulphate with near-infrared hydrophobic dye in the present of Triton X-100, Spectrochim. Acta Part A, 2004, 60 (13): 3173-3179
14. Chang-Qing Zhu, Shu-Juan Zhuo, Hong Zheng, Jin-Long Chen, Dong-Hui Li, Shun-Hua Li, Jin-Gou Xu*, Determination of nucleic acids based on shifting the association equilibrium between heptamethylene cyanine and poly-lysine, Microchim. Acta , 2004, 148 (3-4), 251-257
15. Chang-Qing Zhu, Yu-Qin Wu, Hong Zheng, Jin-Long Chen, Dong-Hui Li, Shun-Hua Li, Jin-Gou Xu*, Determination of nucleic acids by near-infrared Fluorescence quenching of hydrophobic thiacyanine dye in the presence of Triton X-100, Anal.Sci ., 2004, 20: 945-949
16. Chang-Qing Zhu, Yu-Qin Wu, Hong Zheng, Jin-Long Chen, Dong-Hui Li, Shun-Hua Li, Jin-Gou Xu*, Near-infrared fluorimetric determination of protein by shifting the ion-association equilibrium between cationic heptamethylene cyanine and poly-Glutamate, Anal.Lett , 2004, 37 (6): 1115-1127
17. Changqing Zhu, Shujuan Zhuo, Hong Zheng, Jinlong Chen, Donghui Li, Shunhua Li, Jingou Xu*, Determination of nucleic acids based on shifting the association equilibrium between tetracarboxy aluminum phthalocyanine and poly-lysine, Spectrochim. Acta Part A, 2005, 61 (4): 743-748
18. Chang-Qing Zhu, Jin-Long Chen, Hong Zheng, Yu-Qin Wu and Jin-Gou Xu*, A colorimetric method for fluoride determination in aqueous samples based on the hydroxyl deprotection reaction of a cyanine dye , Anal. Chim. Acta, 2005, 539 (1-2 ) : 311-316
19. Changqing Zhu*, Ling Li, Fang Fang, Jinlong Chen, and Yuqin Wu, Functional InP nanocrystals as novel near-infrared fluorescent sensors for mercury ions, Chemistry Letters, 2005, 34 (7): 898-899
20. Jin-Long Chen and Chang-Qing Zhu*,Functionalized cadmium sulfide quantum dots as fluorescence probe for silver ion determination, Anal. Chim. Acta, 2005, 546 (2): 147-153
21. Jin-Long Chen, Shu-Juan Zhuo, Yu-Qing Wu, Fang Fang, Ling Li and Chang-Qing Zhu*, High selective determination iron (II) by its enhancement effet on the fluorescence of pyrene-tetramethylpiperidinyl (TEMPO) as a spin fluorescence probe , Spectrochim. Acta Part A,2006，63: 438-443
22. Fang Fang, Hong Zheng, Ling Li, Yu-Qing Wu, Jin-Long Chen, Shu-Juan Zhuo, and Chang-Qing Zhu*, Determination of nucleic acids with a near infrared cyanine dye using resonance light scattering technique, Spectrochim. Acta Part A, 2006，64: 698-702
23. Yunsheng Xia, Tianlong Zhang, Xuelian Diao, and Changqing Zhu*, Measurable emission color change: size-dependent reversible fluorescence quenching of CdTe quantum dots by molecular oxygen, Chemistry Letters，2007, 36(2), 242-243
24. Xue-Lian Diao, Yun-Sheng Xia, Tian-Long Zhang, Yan Li,and Chang-Qing Zhu*, Fluorescence-detecting cationic surfactants using luminescent CdTe quantum dots as probes, Anal. & Bioanal. Chem., 2007, 388:1191–1197
25. Yun-Sheng Xia, Chun Cao, and Chang-Qing Zhu*, Selectively detect mercury (II) and copper (II) based on the opposite size-dependent fluorescence quenching of CdTe quantum dots, J. Chinese Chemistry, 2007,25:1836—1841
26. Jin-Long Chen, and Chang-Qing Zhu*, Fluorescence enhancement assay for trace iron(II)using Pyr-tempo as a spin label fluorescent probe, Microchim Acta, 2007,156:307–313
27. Yun-Sheng Xia, Chun Cao,and Chang-Qing Zhu*, Two distinct photoluminescence responses of CdTe quantum dots to Ag (I)，Journal of Luminescence, 2008,128: 166–172
28. Tian-Long Zhang, Yun-Sheng Xia, Xue-Lian Diao and Chang-Qing Zhu*, Preparation and formation mechanism of strong violet luminescent CdS quantum dots taking ligand exchange strategy, Journal of Nanoparticle Research, 2008,10:59–67
29. Yunsheng Xia and Changqing Zhu*, Aqueous synthesis of type-II core/shell CdTe/CdSe quantum dots fornear-infrared fluorescent sensing of copper(II), The Analyst,2008,133:928–932
30. Changqing Zhu*, Xin Wang, Yunsheng Xia, Peng Wang, and Yan Li, A pH-triggered reversible aggregation of gold nanorods modified with denatured bovine serum albumin, Chemistry Letters, 2008, 37 (10): 1060-1061
31. Yunsheng Xia* and Changqing Zhu*, Use of surface-modified CdTe quantum dots as fluorescent probes in sensing mercury (II), Talanta, 2008,75:215–221
32. Chang-Qing Zhu*, Peng Wang, Xin Wang, and Yan Li, Facile phosphine-free synthesis of CdSe/ZnS core/shell nanocrystals without precursor injection, Nanoscale Res Lett, 2008,3:213–220
33. Changqing Zhu*, Meigui Liu, Peng Wang, Ming Cao, Chun Cao, Determination of Albumin Using CdS/SiO2 Core/shell Nanoparticles as Fluorescence Probes, Chinese Journal of Chemistry, 2009, 27: 1820–1826
34. Ming Cao, Chun Cao, Menggui Liu，PengWang and Changqing Zhu.Selective fluorometry of cytochromec using glutathione - capped CdTe quantum dots in weakly basic medium. Microchimica Acta 2009, 165 (3-4): 341 – 346
35.Changqing Zhu*, Meigui Liu, Peng Wang, Ming Cao, Chun Cao, Determination of Albumin Using CdS/SiO2 Core/shell Nanoparticles as Fluorescence Probes, Chinese Journal of Chemistry, 2009, 27: 1820–1826.
36.Mingchuan Yu, Yingqiong Jin, Xin Qi, Linjun Bao, Zhangsheng Qian, Changqing Zhu*, Near-Infrared Fluorimetric Determination of Copper(II) Ions Using CdHgTe Nanorods as Probe, Chinese Journal of Chemistry, 2010, 28: 1165–1170
37. Ming Cao, Meigui Liu, ChunCao， Yunsheng Xia， Linjun Bao， Yingqiong Jin， Song Yang, Changqing Zhu*,A simple fluorescence quenching method for berberine determination usingwater soluble CdTe quantum dots as probes. Spectrochimaca Acta Part A: Molecular and Biomolecular Spectroscopy, 2010, 75: 1043-1046
38. Yingqiong Jin, Lilin Sun, Dan Hao, Rui She, Zhangsheng Qian, Changqing Zhu*, Qin Xiao, Peroxyoxalate Chemiluminescence Based on Fluorescent Conjugated Polymer for the Determination of Triton X-100, Chinese Journal of Chemistry., 2011, 29: 575–580.
39. Yunsheng Xia*, Lei Song and Changqing Zhu*, Turn-On and Near-Infrared Fluorescent Sensing for 2,4,6-Trinitrotoluene Based on Hybrid (Gold Nanorod)(Quantum Dots) Assembly, Analytical Chemistry., 2011, 83 (4):1401–1407.
40. Meifang Gui, Linjun Bao, Yunsheng Xia*, Chao Wei, Shengzhou Zhang, Changqing Zhu*, Indication of intracellular physiological pH changes by l-cysteine- coated CdTe quantum dots with an acute alteration in emission color, Biosensors and Bioelectronics, 2011, 30: 324–327.
41. Dahui Tian, Zhangsheng Qian, Yunsheng Xia and Changqing Zhu*, Gold Nanocluster- Based Fluorescent Probes for Near-Infrared and Turn-On Sensing of Glutathione in Living Cells, Langmuir, 2012, 28 (8): 3945–3951.
42. Lilin Sun, Dan Hao, Weili Shen Zhangsheng Qian and Changqing Zhu*, Highly sensitive fluorescent sensor for copper(II) based on amplified fluorescence quenching of a water-soluble NIR emitting conjugated polymer, Microchimica Acta, 2012, 177: 357-564
43. Lilin Sun, Dan Hao, Ping Zhang, Zhangsheng Qian, Weili Shen, Taili Shao, Changqing Zhu*, Indication of critical micelle concentration of nonionic surfactants with large emission change using water-soluble conjugated polymer as molecular light switch, Journal of Luminescence, 2013, 134: 260-265
44. Wenzhu Zhang, Ping Zhang, Shengzhou Zhang, Changqing Zhu*, Label-free and real-time monitoring of trypsin activity in living cells by quantum-dot-based fluorescent sensors, Analytical Methods, 2014, 6: 2499-2505
45. Taili Shao, Guodong Wang, Xuting An, Shujuan Zhuo, Yunsheng Xia, Changqing Zhu*, A reformative oxidation strategy using high concentration nitric acid for enhancing the emission performance of graphene quantum dots, Rsc Advances, 2014, 4: 47977-47981
46. Jinyan Du, Xiawei Dong, Shujuan Zhuo, Weili Shen, Lilin Sun, Changqing Zhu*, Eu(III)-induced room-temperature fast transformation of CdTe nanocrystals into nanorods, Talanta, 2014, 122: 229-233
47. Jinyan Du, Li Ye, Meili Ding, Yuting Chen, Shujuan Zhuo, Changqing Zhu*, Label-free fluorescence polarization detection of pyrophosphate based on 0D/1D fast transformation of CdTe nanostructures, The Analyst, 2014, 139: 3541-3547
48. Xuting An, Shujuan Zhuo, Ping Zhang, Changqing Zhu*, Carbon dots based turn-on fluorescent probes for oxytetracycline hydrochloride sensing, Rsc Advances, 2015, 5: 19853-19858
49. Ping Zhang, Shujuan. Zhuo, Lilin. Sun, Changqing Zhu*, Determination of gamma-globulin at nanogram levels by its quenching effect on the fluorescence of a red emitting conjugated polymer, New Journal of Chemistry, 2015, 39: 4551-4555
50. Tai Li Shao, Ping Zhang, Lin Tang, Shu Juan Zhuo, Chang qing Zhu*, Highly sensitive enzymatic determination of urea based on the pH-dependence of the fluorescence of graphene quantum dots, Microchimica Acta, 2015, 182: 1431-1437
51. Shujuan Zhuo, Jiajia Gong, Ping Zhang, Chang qing Zhu*, High-throughput and rapid fluorescent visualization sensor of urinary citrate by CdTe quantum dots, Talanta,2015, 141: 21-25
52. 朱昌青， 李永新，王伦，鲁米诺 -8- 羟基喹啉 -5- 磺酸 - 镉（ II ） - 过氧化氢化学发光体系的研究, 分析化学，1999，27(6）, 640-643
53. 朱昌青，李东辉，郑洪，核酸对氯化银胶体溶液共振光散射的猝灭作用及其应用，分析化学，2000，28（12）,1485-1488
54. 朱昌青， 李东辉，郑洪，利用四磺基锰酞菁催化酷氨酸与过氧荧光反应测定环境水样中的过氧化氢 , 厦门大学学报（自然科学版），2001，40（1）, 68-73
55. 朱昌青， 李永新，王伦，籍高锰酸钾氧化双乙酰的化学反应测定微量锰， 分析化学 ，1997， 25（4）, 387-390
56. 朱昌青， 李永新，王伦，一种测定微量碘离子的简便偶合化学发光法， 分析化学 ，1997， 25（5）, 570-572
会议论文
第五次亚洲国际分析化学会议:
1. Determination of micro amounts of proteins by their quenching effect on the Rayleigh light scattering of colloidal silver chloride, Chemical journal of Chinese universities, 1999,20(Supplement): 409
2. Determination of nucleic acids by the enhancement of fluorescence in near-IR region, Chemical journal of Chinese universities, 1999, 20(Supplement): 408
3. Near-IR spetrophotometric determination of trace amount of protein in human serum with the synthesized cyanine, Chemical journal of Chinese universities, 1999, 20 (Supplement)：409
第六次全国发光分析学术会议:
1. 过氧化物模拟酶 MnTSPc-L-Tyr-H 2 O 2 体系的催化荧光反应，福州大学学报（自然科学版）， 1999 ， 27 （增刊）： 120-121
2. 人血清中总蛋白的近红外荧光测定，福州大学学报（自然科学版）， 1999 ， 27 （增刊）：118-119
3. 近红外荧光探针法测定核酸的研究，福州大学学报（自然科学版）， 1999 ， 27 （增刊）： 122-123
第八届中国化学会分析化学年会暨第八届全国原子光谱学术会议
-
朱昌青，郑洪，李东辉，李顺华，许金钩，近红外疏水染料荧光猝灭测定非离子表面活性剂SDS,广西师范大学学报,2003，21（1），197
